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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNA3 All Species: 11.21
Human Site: S268 Identified Species: 24.67
UniProt: P22001 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22001 NP_002223.3 575 63842 S268 D E K D Y P A S T S Q D S F E
Chimpanzee Pan troglodytes XP_524797 575 63732 S268 D E K D Y P A S T S Q D S F E
Rhesus Macaque Macaca mulatta XP_001101652 575 63544 S268 D E K D Y P A S P S Q D S F D
Dog Lupus familis XP_547231 467 51847 A169 A A Q E Q P E A A R N G T S G
Cat Felis silvestris
Mouse Mus musculus P16390 528 58545 Q224 D Y P A S P S Q D V F E A A N
Rat Rattus norvegicus P15384 525 58406 D222 Y P A S P S Q D V F E A A N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508752 534 58831 R230 F S F E L L V R F F A C P S K
Chicken Gallus gallus Q7T199 516 58965 S218 F E Y P E S S S A A R G V A L
Frog Xenopus laevis P22739 499 56683 N201 D M H G S G G N Y Y S Y P N S
Zebra Danio Brachydanio rerio XP_002666485 515 58425 T217 I V I F C L E T L P E F R D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08510 655 74175 F252 C L E T L P E F K H Y K V F N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.4 74.4 N.A. 87.4 87.6 N.A. 68.6 56.8 67.1 76 N.A. 53.4 N.A. N.A. N.A.
Protein Similarity: 100 99.6 98.9 76.6 N.A. 89.5 89.3 N.A. 74.4 68.1 74.9 81.5 N.A. 62.7 N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 13.3 0 N.A. 0 13.3 6.6 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 33.3 N.A. 33.3 13.3 N.A. 13.3 33.3 13.3 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 10 0 0 28 10 19 10 10 10 19 19 0 % A
% Cys: 10 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 46 0 0 28 0 0 0 10 10 0 0 28 0 10 19 % D
% Glu: 0 37 10 19 10 0 28 0 0 0 19 10 0 0 19 % E
% Phe: 19 0 10 10 0 0 0 10 10 19 10 10 0 37 0 % F
% Gly: 0 0 0 10 0 10 10 0 0 0 0 19 0 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 28 0 0 0 0 0 10 0 0 10 0 0 10 % K
% Leu: 0 10 0 0 19 19 0 0 10 0 0 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 10 0 0 19 28 % N
% Pro: 0 10 10 10 10 55 0 0 10 10 0 0 19 0 0 % P
% Gln: 0 0 10 0 10 0 10 10 0 0 28 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 10 10 0 10 0 0 % R
% Ser: 0 10 0 10 19 19 19 37 0 28 10 0 28 19 10 % S
% Thr: 0 0 0 10 0 0 0 10 19 0 0 0 10 0 0 % T
% Val: 0 10 0 0 0 0 10 0 10 10 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 10 0 28 0 0 0 10 10 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _